877.944.4786
508.757.4800
info@masshistology.com
7 Lenora Street, Worcester, MA 01607
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Lab Qualifications
Lab Qualifications

Mass Histology Qualifications

Mass Histology Service, Inc. (MHS) was created to fill the need of small to mid-sized biotech companies, researchers, veterinary practices and whoever else is in need of quality microscope slides and histopathology evaluations of their specimens at an affordable price.

Our Facility
Our facility is newly constructed, state of the art and is OSHA-compliant, EPA-compliant and has recently passed a 3-day FDA audit. Our laboratory is also certified by the USDA-APHIS to perform testing on certain exotic animals. We are the holder of permit # 106183 which is the United States veterinary permit allowing us to import and transport controlled materials and organisms and vectors to and from our laboratory. The facility has back-up capability of electrical power generated by a natural gas generator, has a GLP-specific laboratory which has security associability, continuous temperature monitoring, heat, smoke and motion detection security as well as proper ventilation. The GLP office is also secured by lockable doors and fireproof safes.

History

MHS is an established small business located in Worcester, Massachusetts. We have been performing histology and histopathology service for veterinarians, biotechnical, educational and research facilities since 1985. Numerous specimens arrive at our facilities on a daily basis from across the United States as well as several other countries from around the World. We currently employ 15 full or part-time people and 5 consultants and we are projected to perform 95,000 procedures this year. This includes the preparation of H&E, “special” and unstained microscope slides, immunohistochemistry, cytology, frozen sections and reports on pathology. MHS carries a $2,000,000.00 commercial general liability insurance policy. MHS abides to all Federal Equal Employment Opportunity (EEO) Laws and does not discriminate against age, race, color, religion, sex, disabilities or national origin and offers equal pay for equal work.

Overview

Work
All of the work conducted by MHS and its consulting pathologists is performed in accordance with the provisions of the Food & Drug Administration’s Good Laboratory Practice (GLP) regulations 21 CFR, Part 58, Good Laboratory Practice for Non-Clinical Laboratory Studies and all GLP work performed at MHS is audited by an independent Quality Assurance Officer. We have established protocols for chain of custody of specimens, logging-in of specimens, decalcifying boney tissues, tissue trimming, paraffin-processing a variety of tissues, sectioning artifact-free, 5 micron thick sections, routine H&E and all “special” staining as well as the “discovery” of new antibodies in order to determine types of pre-treatments, titrations and length of incubations needed for the antibody to work on specific tissues with the least amount of background (non-specific) staining. In addition to these technical protocols, MHS also maintains safety, continuing education and employee rights manuals.

Specific Capabilities
The following is a brief list of some of the major services offered and performed in-house by MHS. This is by no means a complete list of our capabilities.

Space and Equipment
MHS operates within a 4,000 square foot laboratory and utilizes the following equipment on a routine basis:  

Pick up and delivery
Every day, UPS, FedEx and the U.S. Mail deliver us specimens. UPS is our default outgoing delivery company. Chain of custody forms are used for all GLP studies.   

Key Personnel
Our veterinary pathologists are all board-certified (ACVP) and have many years of full-time experience in toxicological and diagnostic pathology of laboratory and companion animals as well as land and water wild animals. One of our consulting veterinary pathologists is duel-certified in clinical and anatomical veterinary pathology. Our technicians and administrative staff are dedicated, medically-oriented and conscientious employees, most being with MHS for many continuous years. All of our technicians are licensed (or license eligible) by the ASCP (American Society of Clinical Pathologists).   

Past Performance
MHS has been contracted to provide histology or histopathology for many studies, both large and small scale using various animal models. These studies range from “pilot”, to “efficacy” to full scale “GLP”. We also have current contracts with The College of American Pathologists (CAP) as well as the Chief Medical Examiner’s Offices of both Rhode Island and Massachusetts.   

Reports
Each report on pathology generated by MHS is written and signed by a board